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== '''论文著作''' ==

0. Chen, S., Su, X., Zhu, J., Xiao, L., Cong, Y., Yang, L., Du, Z. and Huang, X.# (2023) Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis. EMBO Reports 24:e57440 PMID: 37885348

19. Pan, H., Qin, Y., Zhu, J., Wang, W., Liu, Z., Huang, X., Lam, S-M., Shui, G., Wang, Y., Jiang, Y. and Huang, X.# (2023) Centrins control chicken cone cell lipid droplet dynamics through lipid droplet-localized SPDL1. Developmental Cell 58: 2528-2544 PMID: 37699389

18. Xu, J.*, #, Liu, Z.*, Zhang, J., Chen, S., Wang, W., Zhao, X., Zhen, M. and Huang, X.# (2023) N-end rule-mediated proteasomal degradation of ATGL promotes lipid storage. Diabetes 72:210-222 PMID: 36346641

17. Zhu, J., Lam, S-M., Yang, L., Liang, J., Ding, M., Shui, G. and Huang, X.# (2022) Reduced phosphatidylcholine synthesis suppresses the embryonic lethality of seipin deficiency. Life Metabolism 1:175-189

16. Zhao, X., Wang, W., Yao, Y., Li, X., Huang, X., Wang, Y., Ding, M. and Huang, X.# (2022) An RDH-Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase. EMBO Reports 23:e52669 PMID: 35132760

15. Xu, J.*, #, Chen, S.*, Wang, W., Lam, S-M., Xu, Y., Zhang, S., Pan, H., Liang, J., Huang, X., Wang, Y., Li, T., Jiang, Y., Wang, Y., Ding, M., Shui, G., Yang, H. and Huang, X.# (2022) Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis.Science Bulletin 67:299-314 PMID: 36546079

14. Xu, M., Ding, L., Liang, J., Yang, X., Liu, Y., Wang, Y., Ding, M. and Huang, X.# (2021) NAD kinase sustains lipogenesis and mitochondrial metabolism through fatty acid synthesis. Cell Reports 37:110157 PMID: 34965438

13. Yang, L., Liang, J., Lam, S-M., Yavuz, A., Shui, G., Ding, M. and Huang, X.# (2020) Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration. EMBO Reports 21:e50214 PMID: 33034119

12. Chen, L. #, Chen, X.W. #, Huang, X. #, Song, B.L. #, Wang, Y. #, Wang, Y. # (2019) Regulation of glucose and lipid metabolism in health and disease. Sci China Life Sci. 62:1420-1458 PMID: 31686320 (Review)

11. Yang, X., Liang, J., Ding, L., Li, X., Lam, S-M., Shui, G., Ding, M. and Huang, X.# (2019) Phosphatidylserine synthase regulates cellular homeostasis through distinct metabolic mechanisms. PLoS Genetics 15:e1008548 PMID: 31869331

10. Yao, Y., Li, X., Wang, W., Liu, Z., Chen, J., Ding, M. and Huang, X.# (2018) MRT, functioning with NURF complex, regulates lipid droplet size. Cell Reports 24:2972-2984 PMID: 30208321

9. Ding, L., Yang, X, Tian, H., Liang, J., Zhang, F., Wang, G, Wang, Y., Ding, M., Shui, G and Huang, X.# (2018) Seipin regulates lipid homeostasis by ensuring calcium-dependent mitochondrial metabolism. EMBO J. 37:e97572 PMID: 30049710

8. Zhao, Y.*, Luo, L.*, Xu, J.*, Xin, P., Guo, H., Wu, J., Bai, L., Wang, G., Chu, J., Zuo, J., Yu, H.#, Huang, X.# and Li, J# (2018) Malate transported from chloroplast to mitochondrion triggers production of ROS and PCD in Arabidopsis thaliana. Cell Research 28:448-461 PMID: 29540758

7. Fan, W., Lam, S-M., Xin, J., Yang, X., Liu, Z., Liu, Y., Wang, Y., Shui, G. and Huang, X.# (2017) Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition. PLoS Genetics 13:e1006664 PMID: 28273089

6. Bi, J., Wang, W., Liu, Z., Huang, X., Jiang, Q., Liu, G., Wang, Y. and Huang, X.# (2014) Seipin promotes adipose tissue fat storage through the ER Ca2+-ATPase SERCA. Cell Metabolism 19:861-871 PMID: 24807223

5. Liu, Y., Wang, W., Shui, G.# and Huang, X.# (2014) CDP-diacylglycerol synthetase coordinates cell growth and fat storage through phosphatidylinositol metabolism and the insulin pathway. PLoS Genetics 10:e1004172 PMID: 24603715

4. Bi, J.*, Xiang, Y.*, Chen, H., Liu, Z., Gronke, S., Kuhnlein, R. and Huang, X.# (2012) Opposite and redundant roles of the two Drosophila Perilipins in lipid mobilization. Journal of Cell Science 125:3568-77 PMID: 22505614

3. Tian, Y., Bi, J., Shui, G., Liu, Z., Xiang, Y., Liu, Y., Wenk, M., Yang, H. and Huang, X.# (2011) Tissue-autonomous function of Drosophila Seipin in preventing ectopic lipid droplet formation. PLoS Genetics 7:e1001364 PMID: 21533227

2. Ma, Z., Liu, Z. and Huang, X.# (2010) OSBP- and FAN- mediated sterol requirement for spermatogenesis in Drosophila. Development 137:3775-3784 PMID: 20943709

1. Chen, H., Liu, Z. and Huang, X.# (2010) Drosophila models of peroxisomal biogenesis disorder: Peroxins are required for spermatogenesis and very long chain fatty acid metabolism. Human Molecular Genetics 19:494-505 PMID: 19933170

[[分类:人员]]
[[分类:研究人员]]
[[分类:生物多样性保护专家]]

←上一版本		2025年9月23日 (二) 14:33的版本
第1行：		第1行：

			== '''性别''' ==
			男


			== '''工作单位''' ==
			中国科学院遗传与发育生物学研究所


			== '''职称/职务''' ==
			研究员


			== '''主要研究方向''' ==
			脂代谢调控


			== '''工作年限（从事该领域研究的起始时间）''' ==
			19年（起始：2006）


	== '''论文著作''' ==		== '''论文著作''' ==


	0. Chen, S., Su, X., Zhu, J., Xiao, L., Cong, Y., Yang, L., Du, Z. ~~and Huang~~, X.# (2023) Metabolic plasticity sustains the robustness ~~of Caenorhabditis elegans embryogenesis~~. ~~EMBO Reports 24~~:e57440 PMID: 37885348		0. Chen, S., Su, X., Zhu, J., Xiao, L., Cong, Y., Yang, L., Du, Z. and Huang, X.# (2023) Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis. EMBO Reports 24:e57440 PMID: 37885348

	19. Pan, H., Qin, Y., Zhu, J., Wang, W., Liu, Z., Huang, X., Lam, S-M., Shui, G., Wang, Y., Jiang, Y. ~~and Huang~~, X.# (2023) Centrins control chicken cone cell lipid droplet dynamics through lipid droplet-localized SPDL1. ~~Developmental Cell 58~~: 2528-2544 PMID: 37699389		19. Pan, H., Qin, Y., Zhu, J., Wang, W., Liu, Z., Huang, X., Lam, S-M., Shui, G., Wang, Y., Jiang, Y. and Huang, X.# (2023) Centrins control chicken cone cell lipid droplet dynamics through lipid droplet-localized SPDL1. Developmental Cell 58: 2528-2544 PMID: 37699389

	18. Xu, J., #, Liu, Z., Zhang, J., Chen, S., Wang, W., Zhao, X., Zhen, M. ~~and Huang~~, X.# (2023) N-end rule-mediated proteasomal degradation of ATGL promotes lipid storage. ~~Diabetes 72~~:210-222 PMID: 36346641		18. Xu, J., #, Liu, Z., Zhang, J., Chen, S., Wang, W., Zhao, X., Zhen, M. and Huang, X.# (2023) N-end rule-mediated proteasomal degradation of ATGL promotes lipid storage. Diabetes 72:210-222 PMID: 36346641

	17. Zhu, J., Lam, S-M., Yang, L., Liang, J., Ding, M., Shui, G. ~~and Huang~~, X.# (2022) Reduced phosphatidylcholine synthesis suppresses the embryonic lethality of seipin deficiency. ~~Life Metabolism 1~~:175-189		17. Zhu, J., Lam, S-M., Yang, L., Liang, J., Ding, M., Shui, G. and Huang, X.# (2022) Reduced phosphatidylcholine synthesis suppresses the embryonic lethality of seipin deficiency. Life Metabolism 1:175-189

	16. Zhao, X., Wang, W., Yao, Y., Li, X., Huang, X., Wang, Y., Ding, M. ~~and Huang~~, X.# (2022) An RDH-Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase. ~~EMBO Reports 23~~:e52669 PMID: 35132760		16. Zhao, X., Wang, W., Yao, Y., Li, X., Huang, X., Wang, Y., Ding, M. and Huang, X.# (2022) An RDH-Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase. EMBO Reports 23:e52669 PMID: 35132760

	15. Xu, J., #, Chen, S., Wang, W., Lam, S-M., Xu, Y., Zhang, S., Pan, H., Liang, J., Huang, X., Wang, Y., Li, T., Jiang, Y., Wang, Y., Ding, M., Shui, G., Yang, H. ~~and Huang~~, X.# (2022) Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis.Science ~~Bulletin 67~~:299-314 PMID: 36546079		15. Xu, J., #, Chen, S., Wang, W., Lam, S-M., Xu, Y., Zhang, S., Pan, H., Liang, J., Huang, X., Wang, Y., Li, T., Jiang, Y., Wang, Y., Ding, M., Shui, G., Yang, H. and Huang, X.# (2022) Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis.Science Bulletin 67:299-314 PMID: 36546079

	14. Xu, M., Ding, L., Liang, J., Yang, X., Liu, Y., Wang, Y., Ding, M. ~~and Huang~~, X.# (2021) NAD kinase sustains lipogenesis and mitochondrial metabolism through fatty acid synthesis. ~~Cell Reports 37~~:110157 PMID: 34965438		14. Xu, M., Ding, L., Liang, J., Yang, X., Liu, Y., Wang, Y., Ding, M. and Huang, X.# (2021) NAD kinase sustains lipogenesis and mitochondrial metabolism through fatty acid synthesis. Cell Reports 37:110157 PMID: 34965438

	13. Yang, L., Liang, J., Lam, S-M., Yavuz, A., Shui, G., Ding, M. ~~and Huang~~, X.# (2020) Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration. ~~EMBO Reports 21~~:e50214 PMID: 33034119		13. Yang, L., Liang, J., Lam, S-M., Yavuz, A., Shui, G., Ding, M. and Huang, X.# (2020) Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration. EMBO Reports 21:e50214 PMID: 33034119

	12. Chen, L. #, Chen, X.W. #, ~~Huang~~, X. #, Song, B.L. #, Wang, Y. #, Wang, Y. # (2019) Regulation of glucose and lipid metabolism in health and disease. ~~Sci~~ China Life Sci. 62:1420-1458 PMID: 31686320 (Review)		12. Chen, L. #, Chen, X.W. #, Huang, X. #, Song, B.L. #, Wang, Y. #, Wang, Y. # (2019) Regulation of glucose and lipid metabolism in health and disease. Sci China Life Sci. 62:1420-1458 PMID: 31686320 (Review)

	11. Yang, X., Liang, J., Ding, L., Li, X., Lam, S-M., Shui, G., Ding, M. ~~and Huang~~, X.# (2019) Phosphatidylserine synthase regulates cellular homeostasis through distinct metabolic mechanisms. ~~PLoS Genetics 15~~:e1008548 PMID: 31869331		11. Yang, X., Liang, J., Ding, L., Li, X., Lam, S-M., Shui, G., Ding, M. and Huang, X.# (2019) Phosphatidylserine synthase regulates cellular homeostasis through distinct metabolic mechanisms. PLoS Genetics 15:e1008548 PMID: 31869331

	10. Yao, Y., Li, X., Wang, W., Liu, Z., Chen, J., Ding, M. ~~and Huang~~, X.# (2018) MRT, functioning with NURF complex, regulates lipid droplet size. ~~Cell Reports 24~~:2972-2984 PMID: 30208321		10. Yao, Y., Li, X., Wang, W., Liu, Z., Chen, J., Ding, M. and Huang, X.# (2018) MRT, functioning with NURF complex, regulates lipid droplet size. Cell Reports 24:2972-2984 PMID: 30208321

	9. Ding, L., Yang, X, Tian, H., Liang, J., Zhang, F., Wang, G, Wang, Y., Ding, M., Shui, G ~~and Huang~~, X.# (2018) Seipin regulates lipid homeostasis by ensuring calcium-dependent mitochondrial metabolism. ~~EMBO~~ J. 37:~~e97572 PMID~~: 30049710		9. Ding, L., Yang, X, Tian, H., Liang, J., Zhang, F., Wang, G, Wang, Y., Ding, M., Shui, G and Huang, X.# (2018) Seipin regulates lipid homeostasis by ensuring calcium-dependent mitochondrial metabolism. EMBO J. 37:e97572 PMID: 30049710

	8. Zhao, Y., Luo, L., Xu, J.*, Xin, P., Guo, H., Wu, J., Bai, L., Wang, G., Chu, J., Zuo, J., Yu, H.#, ~~Huang~~, X.# ~~and~~ Li, J# (2018) Malate transported from chloroplast to mitochondrion triggers production of ROS and PCD ~~in Arabidopsis~~ thaliana. ~~Cell Research 28~~:448-461 PMID: 29540758		8. Zhao, Y., Luo, L., Xu, J.*, Xin, P., Guo, H., Wu, J., Bai, L., Wang, G., Chu, J., Zuo, J., Yu, H.#, Huang, X.# and Li, J# (2018) Malate transported from chloroplast to mitochondrion triggers production of ROS and PCD in Arabidopsis thaliana. Cell Research 28:448-461 PMID: 29540758

	7. Fan, W., Lam, S-M., Xin, J., Yang, X., Liu, Z., Liu, Y., Wang, Y., Shui, G. ~~and Huang~~, X.# (2017) ~~Drosophila TRF2~~ and TAF9 regulate lipid droplet size and phospholipid fatty acid composition. ~~PLoS Genetics 13~~:e1006664 PMID: 28273089		7. Fan, W., Lam, S-M., Xin, J., Yang, X., Liu, Z., Liu, Y., Wang, Y., Shui, G. and Huang, X.# (2017) Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition. PLoS Genetics 13:e1006664 PMID: 28273089

	6. Bi, J., Wang, W., Liu, Z., Huang, X., Jiang, Q., Liu, G., Wang, Y. ~~and Huang~~, X.# (2014) Seipin promotes adipose tissue fat storage through the ER Ca2+-ATPase SERCA. ~~Cell Metabolism 19~~:861-871 PMID: 24807223		6. Bi, J., Wang, W., Liu, Z., Huang, X., Jiang, Q., Liu, G., Wang, Y. and Huang, X.# (2014) Seipin promotes adipose tissue fat storage through the ER Ca2+-ATPase SERCA. Cell Metabolism 19:861-871 PMID: 24807223

	5. Liu, Y., Wang, W., Shui, G.# ~~and Huang~~, X.# (2014) CDP-diacylglycerol synthetase coordinates cell growth and fat storage through phosphatidylinositol metabolism and the insulin pathway. ~~PLoS Genetics 10~~:e1004172 PMID: 24603715		5. Liu, Y., Wang, W., Shui, G.# and Huang, X.# (2014) CDP-diacylglycerol synthetase coordinates cell growth and fat storage through phosphatidylinositol metabolism and the insulin pathway. PLoS Genetics 10:e1004172 PMID: 24603715

	4. Bi, J., Xiang, Y., Chen, H., Liu, Z., Gronke, S., Kuhnlein, R. ~~and Huang~~, X.# (2012) Opposite and redundant roles of the ~~two Drosophila Perilipins~~ in lipid mobilization. ~~Journal~~ of Cell ~~Science 125~~:3568-77 PMID: 22505614		4. Bi, J., Xiang, Y., Chen, H., Liu, Z., Gronke, S., Kuhnlein, R. and Huang, X.# (2012) Opposite and redundant roles of the two Drosophila Perilipins in lipid mobilization. Journal of Cell Science 125:3568-77 PMID: 22505614

	3. Tian, Y., Bi, J., Shui, G., Liu, Z., Xiang, Y., Liu, Y., Wenk, M., Yang, H. ~~and Huang~~, X.# (2011) Tissue-autonomous function ~~of Drosophila Seipin~~ in preventing ectopic lipid droplet formation. ~~PLoS Genetics 7~~:e1001364 PMID: 21533227		3. Tian, Y., Bi, J., Shui, G., Liu, Z., Xiang, Y., Liu, Y., Wenk, M., Yang, H. and Huang, X.# (2011) Tissue-autonomous function of Drosophila Seipin in preventing ectopic lipid droplet formation. PLoS Genetics 7:e1001364 PMID: 21533227

	2. Ma, Z., Liu, Z. ~~and Huang~~, X.# (2010) OSBP- and FAN- mediated sterol requirement for spermatogenesis ~~in Drosophila~~. ~~Development 137~~:3775-3784 PMID: 20943709		2. Ma, Z., Liu, Z. and Huang, X.# (2010) OSBP- and FAN- mediated sterol requirement for spermatogenesis in Drosophila. Development 137:3775-3784 PMID: 20943709

	1. Chen, H., Liu, Z. ~~and Huang~~, X.# (2010) ~~Drosophila models~~ of peroxisomal biogenesis disorder: Peroxins are required for spermatogenesis and very long chain fatty acid metabolism. ~~Human~~ Molecular ~~Genetics 19~~:494-505 PMID: 19933170		1. Chen, H., Liu, Z. and Huang, X.# (2010) Drosophila models of peroxisomal biogenesis disorder: Peroxins are required for spermatogenesis and very long chain fatty acid metabolism. Human Molecular Genetics 19:494-505 PMID: 19933170

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