李伟：修订间差异

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== '''代表性文章''' ==
== '''性别''' ==
女




[1] Li Wei, Zuo Xueyan, Liu Zhijun, Nie Leichao, Li Huazhe, Wang Junjie, Dou Zhiguo, Cai Yang, Zhai Xiajie, Cui Lijuan*. Predictions of Spartina alterniflora leaf functional traits based on hyperspectral data and machine learning models. European Journal of Remote Sensing. 2023. 57:1, 2294951.
== '''工作单位''' ==
中国水产科学研究院


[2] Li Wei, Dou Zhiguo, Cui Lijuan*, Wang Rumiao, Zhao Zhijiang, Cui Shifeng, Lei Yinru, Li Jing, Zhao Xinsheng, Zhai Xiajie. Suitability of hyperspectral data for monitoring nitrogen and phosphorus contents in constructed wetlands. Remote sensing letters. 2020,11(5):495-504.


[3] Li Wei, Dou Zhiguo, Cui Lijuan*, Zhao Xinsheng, Zhang Manyin, Zhang Yan, Gao Changjun, Yang Zheng, Lei Yinru, Pan Xu. Soil fauna diversity at different stages of reed restoration in a lakeshore wetland at Lake Taihu, China. Ecosystem Health and Sustainability. 2020,6(1):1722034.
== '''职称/职务''' ==
副研究员


[4] Li Wei, Cui Lijuan*, Zhang Yan, Zhang Manyin, Zhao Xinsheng, Wang Yifei. Statistical modeling of phosphorus removal in horizontal subsurface constructed wetland[J]. Wetlands, 2014, 34(3):427-437.


[5] Li Wei, Cui Lijuan*, Zhang Manyin, Wang Yifei, Zhang Yaqiong, Lei Yinru, Zhao Xinsheng. Effect of mangrove restoration on crab burrow density in Luoyangjiang Estuary, China [J]. Forest Ecosystems, 2015,2:21.
== '''主要研究方向''' ==
水产动物种质资源评价与保护、水产动物遗传资源开发与利用


[6] Cui Lijuan, Li Wei*, Zhao Xinsheng, Zhang Manyin, Lei Yinru, Zhang Yan, Gao Changjun, Kang Xiaoming, Sun Baodi, Zhang Yaqiong. The relationship between standing vegetation and the soil seed bank along the shores of Lake Taihu, China [J]. Ecological Engineering, 2016, 96:45–54.


[7] Tang Xiying, Dou Zhiguo, Cui Lijuan, Liu Zhijun, Gao Changjun, Wang Junjie, Li Jing, Lei Yinru, Zhao Xinsheng, Zhai Xiajie, Li Wei*. Hyperspectral prediction of mangrove leaf stoichiometries in different restoration areas based on machine learning models. Journal of Applied Remote Sensing. 2022, 16(3): 034525.
== '''代表论著''' ==


[8] Li Huazhe, Tang Xiying, Cui Lijuan, Zhai Xiajie, Wang Junjie, Zhao Xinsheng, Li Jing, Lei Yinru, Wang Jinzhi, Wang Rumiao, Li Wei*. Estimating aboveground biomass of wetland plant communities from hyperspectral data based on Fractional-Order Derivatives and machine learning. Remote Sensing, 2024, 16, 3011.


[9] Zou Yuhan, Tang Xiying, Cui Lijuan, Li Huazhe, Lei Yinru, Zhao Xinsheng, Zhai Xiajie, Li Jing, Wang Jinzhi, Wang Rumiao, Li Wei*. Analysis of coupled wetland soil–plant ecological stoichiometric characteristics of carbon, nitrogen, and phosphorus under different disturbance intensities. Plant and Soil. 2024.DOI:10.1007/s11104-024-07031-9.
Chen Y#, Luo S#, Hu Y#, Mao B#, Wang X#, Lu Z#, Shan Q, Zhang J, Wang S, Feng G, Wang C, Liang C, Tang N, Niu R, Wang J, Han J, Yang N, Wang H, Zhou Q*, Li W*. All-RNA-mediated targeted gene integration in mammalian cells with rationally engineered R2 retrotransposons. Cell 2024 Aug 22;187(17):4674-4689.e18. doi: 10.1016/j.cell.2024.06.020. Epub 2024 Jul 8.


[10] Wang Zecheng, Zhao Xinsheng, Cui Lijuan*, Lei Yinru, Zhai Xiajie, Wang Jinzhi, Li Jing, Wang Rumiao, Li Wei*. Identification and Optimization of Urban Wetland Ecological Networks in Highly Urbanized Areas: A Case Study of Haidian District, Beijing. Ecological Indicators, 2025, 170 :113028.
Cui T#, Cai B#, Tian Y, Liu X, Liang C, Gao Q, Li B, Ding Y, Li R, Zhou Q, Li W*, Teng F*. Therapeutic In Vivo Gene Editing Achieved by a Hypercompact CRISPR-Cas12f1 System Delivered with All-in-One Adeno-Associated Virus. Advanced Science (Weinh) 2024 May;11(19):e2308095. doi: 10.1002/advs.202308095. Epub 2024 Feb 26. (Cover story)


Wang C#, Fang S#, Chen Y#, Tang N, Jiao G, Hu Y, Li J, Shan Q, Wang X, Feng G, Zhou Q*, Li W*. High-efficiency targeted transgene integration via primed micro-homologues. Cell Discovery 2023 Jul 4;9(1):69. doi: 10.1038/s41421-023-00552-0.


== '''获奖''' ==
Wang LB#, Li ZK#, Wang LY#, Xu K#, Ji TT#, Mao YH, Ma SN, Liu T, Tu CF, Zhao Q, Fan XN, Liu C, Wang LY, Shu YJ, Yang N, Zhou Q*, Li W*. A sustainable mouse karyotype created by programmed chromosome fusion. Science 2022 Aug 26;377(6609):967-975. doi: 10.1126/science.abm1964. Epub 2022 Aug 25.


Chen Y#, Hu Y#, Wang X#, Luo S, Yang N, Chen Y, Li Z, Zhou Q*, Li W*. Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing. Innovation (Camb). 2022 May 26;3(4):100264. doi: 10.1016/j.xinn.2022.100264.


[1] 国家科学技术进步奖二等奖.2017年.（排名4）
He ZQ#, Li YH#, Feng GH#, Yuan XW#, Lu ZB#, Dai M, Hu YP, Zhang Y, Zhou Q*, Li W*. Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons. Advanced Science (Weinh). 2022 May;9(13):e2104682. doi: 10.1002/advs.202104682.


[2] 北京市园林绿化科学技术奖一等奖. 2014年.（排名1）
Hu Y#, Chen Y#, Xu J#, Wang X, Luo S, Mao B, Zhou Q*, Li W*. Metagenomic discovery of novel CRISPR-Cas13 systems. Cell Discovery 2022 Oct 11;8(1):107. doi: 10.1038/s41421-022-00464-5.


[3] 第六届梁希科普奖二等奖.2017年.（排名1）
Guo L, Sun X, Wang X, Liang C, Jiang H, Gao Q, Dai M, Qu B, Fang S, Mao Y, Chen Y, Feng G, Gu Q, Wang RR*, Zhou Q*, Li W*. SARS-CoV-2 detection with CRISPR diagnostics. Cell Discovery 2020 May 19;6:34. doi: 10.1038/s41421-020-0174-y.


[4] 第五届梁希青年论文一等奖.（排名1）
Wang LY#, Li ZK#, Wang LB#, Liu C#, Sun XH#, Feng GH#, Wang JQ, Li YF, Qiao LY, Nie H, Jiang LY, Sun H, Xie YL, Ma SN, Wan HF, Lu FL*, Li W*, Zhou Q*. Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer. Cell Stem Cell 2020 Aug 6;27(2):315-325.e5. doi: 10.1016/j.stem.2020.05.014.


[5] 中国林科院重大科技成果奖. 2022年.（排名4）
Qu B#, Wu S#, Jiao G#, Zou X#, Li Z#, Guo L#, Sun X, Huang C, Sun Z, Zhang Y, Li H, Zhou Q, Sui R*, Li W*. Treating Bietti crystalline dystrophy in a high-fat diet-exacerbated murine model using gene therapy. Gene Therapy 2020 Aug; 27(7-8):370-382.doi: 10.1038/s41434-020-0159-3.


[6] 北京林学会林业科技进步奖一等奖. 2021年.（排名5）
Mao J#, Xu K#, Han J#, Feng G, Zhang Y*, Li W*. Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon. Protein & Cell 2020 Jun;11(6):452-457. doi: 10.1007/s13238-020-00702-0.


[7] 中国林科院重大科技成果奖.2019年.（排名8）
Teng F#, Guo L#, Cui T, Wang XG, Xu K, Gao Q, Zhou Q*, Li W*. CDetection: CRISPR-Cas12b-based DNA detection with sub-attomolar sensitivity and single-base specificity. Genome Biology 2019b Jul 1;20(1):132. doi: 10.1186/s13059-019-1742-z.


[8] 第十四届梁希林业科学技术奖科技进步奖一等奖. 2024年.（排名8）
Teng F#, Li J#, Cui T#, Xu K, Guo L, Gao Q, Feng G, Chen C, Han D, Zhou Q*, Li W*. Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds. Genome Biology 2019a Feb 5;20(1):15. doi: 10.1186/s13059-019-1620-8.


著作：
Li Y#, Wang L#, Zhang L#, He Z#, Feng G, Sun H, Wang J, Li Z, Liu C, Han J, Mao J, Li P, Yuan X, Jiang L, Zhang Y*, Zhou Q*, Li W*. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. Journal Of Cell Biology 2019 May 6;218(5):1553-1563. doi: 10.1083/jcb.201808088.


[1] 李伟,崔丽娟.北京湿地中常见植物知多少.中国林业出版社.2019
Wang J#, Wang L#, Feng G#, Wang Y#, Li Y, Li X, Liu C, Jiao G, Huang C, Shi J, Zhou T, Chen Q, Liu Z, Li W*, Zhou Q*. Asymmetric expression of LincGET biases cell fate in two-cell mouse embryos. Cell 2018 Dec 13;175(7):1887-1901.e18. doi: 10.1016/j.cell.2018.11.039.


[2] 李伟,崔丽娟,邓侃,张颖,李海燕.中国湿地.科学普及出版社.2016
Teng F#, Cui T#, Feng G, Guo L, Xu K, Gao Q, Li T, Li J, Zhou Q, Li W*. Repurposing CRISPR-Cas12b for mammalian genome engineering. Cell Discovery 2018 Nov 27;4:63. doi: 10.1038/s41421-018-0069-3.


[3] 崔丽娟,李伟,赵欣胜,高常军.太湖流域湿地生态状况及其评价研究.中国林业出版社.2019
Zhang W#, Wan H#, Feng G#, Qu J#, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W*, Liu G*, Hu B*. SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Nature 2018 Aug;560(7720):661-665. doi: 10.1038/s41586-018-0437-z.


[4] 崔丽娟,康晓明,张曼胤,李伟.中国滨海湿地生态系统功能及服务评价.中国林业出版社.2019
Li ZK#, Wang LY#, Wang LB#, Feng GH#, Yuan XW#, Liu C, Xu K, Li YH, Wan HF, Zhang Y, Li YF, Li X, Li W*, Zhou Q*, Hu BY*. Generation of bimaternal and bipaternal mice from hypomethylated haploid escs with imprinting region deletions. Cell Stem Cell 2018 Nov 1;23(5):665-676.e4. doi: 10.1016/j.stem.2018.09.004.


[5] 马琼芳,李伟,燕红,赵欣胜.吉林省湿地生态系统服务功能评估.东北林业大学出版社. 2021
Xu K#, Yang Y#, Feng GH#, Sun BF#, Chen JQ#, Li YF, Chen YS, Zhang XX, Wang CX, Jiang LY, Liu C, Zhang ZY, Wang XJ, Zhou Q*, Yang YG*, Li W*. Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation. Cell Research 2017 Sep;27(9):1100-1114. doi: 10.1038/cr.2017.100. (Cover story)


[6] 董鸣,崔丽娟主编. 赵彩云,吴明,李伟,宋垚彬副主编. 滨海滩涂湿地生态系统生态学研究.科学出版社. 2021
Li X#, Cui XL#, Wang JQ#, Wang YK, Li YF, Wang LY, Wan HF, Li TD, Feng GH, Shuai L, Li ZK, Gu Q, Hao J, Wang L, Zhao XY, Liu ZH, Wang XJ, Li W*, Zhou Q*. Generation and application of mouse-rat allodiploid embryonic stem cells. Cell 2016 Jan 14;164(1-2):279-292. doi: 10.1016/j.cell.2015.11.035.


专利：
Wan HF#, Feng CJ#, Teng F#, Yang SH#, Hu BY, Niu YY, Xiang P, Fang WZ, Ji WZ, Li W*, Zhao XY*, Zhou Q*. One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system. Cell Research 2015 Feb;25(2):258-261. doi: 10.1038/cr.2014.158.


[1]      Li Wei, Cui Lijuan, Dou Zhiguo, et al. Device and method for harvesting wind-borne of wetland plant. 美国国家发明专利.2020
Li W#, Li X#, Li TD#, Jiang MG#, Wan HF, Luo GZ, Feng CJ, Cui XL, Teng F, Yuan Y, Zhou Q, Gu Q, Shuai L, Sha JH, Xiao YM, Wang L, Liu ZH, Wang XJ, Zhao XY, Zhou Q*. Genetic modification and screening in rat using haploid embryonic stem cells. Cell Stem Cell 2014 Mar 6;14(3):404-414. doi: 10.1016/j.stem.2013.11.016.


[2]      Li Wei, Dou Zhiguo, Cui Lijuan, et al. A capture device for hydraulically transmitted wetland plant seed and method of using the same.加拿大国家发明专利. 2020
Li W#, Teng F#, Li T, Zhou Q*. Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nature Biotechnology 2013 Aug;31(8):684-686. doi: 10.1038/nbt.2652.


[3]      李伟,崔丽娟,张亚琼,等.用于人工湿地植物的根系测量装置及方法.国家发明专利.2016
Li W#, Shuai L#, Wan H#, Dong M#, Wang M, Sang L, Feng C, Luo GZ, Li T, Li X, Wang L, Zheng QY, Sheng C, Wu HJ, Liu Z, Liu L, Wang L, Wang XJ, Zhao XY*, Zhou Q*. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature 2012 Oct 18;490(7420):407-411. doi: 10.1038/nature11435.


[4]      李伟,崔丽娟,张岩,等.一种人工水平潜流湿地及其防堵塞沉淀池及防堵塞方法.国家发明专利.2017
Zhao XY#, Li W#, Lv Z#, Liu L, Tong M, Hai T, Hao J, Guo CL, Ma QW, Wang L, Zeng F*, Zhou Q*. iPS cells produce viable mice through tetraploid complementation. Nature 2009 Sep 3;461(7260):86-90. doi: 10.1038/nature08267.




2025年9月23日 (二) 17:13的最新版本

性别

女


工作单位

中国水产科学研究院


职称/职务

副研究员


主要研究方向

水产动物种质资源评价与保护、水产动物遗传资源开发与利用


代表论著

Chen Y#, Luo S#, Hu Y#, Mao B#, Wang X#, Lu Z#, Shan Q, Zhang J, Wang S, Feng G, Wang C, Liang C, Tang N, Niu R, Wang J, Han J, Yang N, Wang H, Zhou Q*, Li W*. All-RNA-mediated targeted gene integration in mammalian cells with rationally engineered R2 retrotransposons. Cell 2024 Aug 22;187(17):4674-4689.e18. doi: 10.1016/j.cell.2024.06.020. Epub 2024 Jul 8.

Cui T#, Cai B#, Tian Y, Liu X, Liang C, Gao Q, Li B, Ding Y, Li R, Zhou Q, Li W*, Teng F*. Therapeutic In Vivo Gene Editing Achieved by a Hypercompact CRISPR-Cas12f1 System Delivered with All-in-One Adeno-Associated Virus. Advanced Science (Weinh) 2024 May;11(19):e2308095. doi: 10.1002/advs.202308095. Epub 2024 Feb 26. (Cover story)

Wang C#, Fang S#, Chen Y#, Tang N, Jiao G, Hu Y, Li J, Shan Q, Wang X, Feng G, Zhou Q*, Li W*. High-efficiency targeted transgene integration via primed micro-homologues. Cell Discovery 2023 Jul 4;9(1):69. doi: 10.1038/s41421-023-00552-0.

Wang LB#, Li ZK#, Wang LY#, Xu K#, Ji TT#, Mao YH, Ma SN, Liu T, Tu CF, Zhao Q, Fan XN, Liu C, Wang LY, Shu YJ, Yang N, Zhou Q*, Li W*. A sustainable mouse karyotype created by programmed chromosome fusion. Science 2022 Aug 26;377(6609):967-975. doi: 10.1126/science.abm1964. Epub 2022 Aug 25.

Chen Y#, Hu Y#, Wang X#, Luo S, Yang N, Chen Y, Li Z, Zhou Q*, Li W*. Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing. Innovation (Camb). 2022 May 26;3(4):100264. doi: 10.1016/j.xinn.2022.100264.

He ZQ#, Li YH#, Feng GH#, Yuan XW#, Lu ZB#, Dai M, Hu YP, Zhang Y, Zhou Q*, Li W*. Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons. Advanced Science (Weinh). 2022 May;9(13):e2104682. doi: 10.1002/advs.202104682.

Hu Y#, Chen Y#, Xu J#, Wang X, Luo S, Mao B, Zhou Q*, Li W*. Metagenomic discovery of novel CRISPR-Cas13 systems. Cell Discovery 2022 Oct 11;8(1):107. doi: 10.1038/s41421-022-00464-5.

Guo L, Sun X, Wang X, Liang C, Jiang H, Gao Q, Dai M, Qu B, Fang S, Mao Y, Chen Y, Feng G, Gu Q, Wang RR*, Zhou Q*, Li W*. SARS-CoV-2 detection with CRISPR diagnostics. Cell Discovery 2020 May 19;6:34. doi: 10.1038/s41421-020-0174-y.

Wang LY#, Li ZK#, Wang LB#, Liu C#, Sun XH#, Feng GH#, Wang JQ, Li YF, Qiao LY, Nie H, Jiang LY, Sun H, Xie YL, Ma SN, Wan HF, Lu FL*, Li W*, Zhou Q*. Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer. Cell Stem Cell 2020 Aug 6;27(2):315-325.e5. doi: 10.1016/j.stem.2020.05.014.

Qu B#, Wu S#, Jiao G#, Zou X#, Li Z#, Guo L#, Sun X, Huang C, Sun Z, Zhang Y, Li H, Zhou Q, Sui R*, Li W*. Treating Bietti crystalline dystrophy in a high-fat diet-exacerbated murine model using gene therapy. Gene Therapy 2020 Aug; 27(7-8):370-382.doi: 10.1038/s41434-020-0159-3.

Mao J#, Xu K#, Han J#, Feng G, Zhang Y*, Li W*. Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon. Protein & Cell 2020 Jun;11(6):452-457. doi: 10.1007/s13238-020-00702-0.

Teng F#, Guo L#, Cui T, Wang XG, Xu K, Gao Q, Zhou Q*, Li W*. CDetection: CRISPR-Cas12b-based DNA detection with sub-attomolar sensitivity and single-base specificity. Genome Biology 2019b Jul 1;20(1):132. doi: 10.1186/s13059-019-1742-z.

Teng F#, Li J#, Cui T#, Xu K, Guo L, Gao Q, Feng G, Chen C, Han D, Zhou Q*, Li W*. Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds. Genome Biology 2019a Feb 5;20(1):15. doi: 10.1186/s13059-019-1620-8.

Li Y#, Wang L#, Zhang L#, He Z#, Feng G, Sun H, Wang J, Li Z, Liu C, Han J, Mao J, Li P, Yuan X, Jiang L, Zhang Y*, Zhou Q*, Li W*. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. Journal Of Cell Biology 2019 May 6;218(5):1553-1563. doi: 10.1083/jcb.201808088.

Wang J#, Wang L#, Feng G#, Wang Y#, Li Y, Li X, Liu C, Jiao G, Huang C, Shi J, Zhou T, Chen Q, Liu Z, Li W*, Zhou Q*. Asymmetric expression of LincGET biases cell fate in two-cell mouse embryos. Cell 2018 Dec 13;175(7):1887-1901.e18. doi: 10.1016/j.cell.2018.11.039.

Teng F#, Cui T#, Feng G, Guo L, Xu K, Gao Q, Li T, Li J, Zhou Q, Li W*. Repurposing CRISPR-Cas12b for mammalian genome engineering. Cell Discovery 2018 Nov 27;4:63. doi: 10.1038/s41421-018-0069-3.

Zhang W#, Wan H#, Feng G#, Qu J#, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W*, Liu G*, Hu B*. SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Nature 2018 Aug;560(7720):661-665. doi: 10.1038/s41586-018-0437-z.

Li ZK#, Wang LY#, Wang LB#, Feng GH#, Yuan XW#, Liu C, Xu K, Li YH, Wan HF, Zhang Y, Li YF, Li X, Li W*, Zhou Q*, Hu BY*. Generation of bimaternal and bipaternal mice from hypomethylated haploid escs with imprinting region deletions. Cell Stem Cell 2018 Nov 1;23(5):665-676.e4. doi: 10.1016/j.stem.2018.09.004.

Xu K#, Yang Y#, Feng GH#, Sun BF#, Chen JQ#, Li YF, Chen YS, Zhang XX, Wang CX, Jiang LY, Liu C, Zhang ZY, Wang XJ, Zhou Q*, Yang YG*, Li W*. Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation. Cell Research 2017 Sep;27(9):1100-1114. doi: 10.1038/cr.2017.100. (Cover story)

Li X#, Cui XL#, Wang JQ#, Wang YK, Li YF, Wang LY, Wan HF, Li TD, Feng GH, Shuai L, Li ZK, Gu Q, Hao J, Wang L, Zhao XY, Liu ZH, Wang XJ, Li W*, Zhou Q*. Generation and application of mouse-rat allodiploid embryonic stem cells. Cell 2016 Jan 14;164(1-2):279-292. doi: 10.1016/j.cell.2015.11.035.

Wan HF#, Feng CJ#, Teng F#, Yang SH#, Hu BY, Niu YY, Xiang P, Fang WZ, Ji WZ, Li W*, Zhao XY*, Zhou Q*. One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system. Cell Research 2015 Feb;25(2):258-261. doi: 10.1038/cr.2014.158.

Li W#, Li X#, Li TD#, Jiang MG#, Wan HF, Luo GZ, Feng CJ, Cui XL, Teng F, Yuan Y, Zhou Q, Gu Q, Shuai L, Sha JH, Xiao YM, Wang L, Liu ZH, Wang XJ, Zhao XY, Zhou Q*. Genetic modification and screening in rat using haploid embryonic stem cells. Cell Stem Cell 2014 Mar 6;14(3):404-414. doi: 10.1016/j.stem.2013.11.016.

Li W#, Teng F#, Li T, Zhou Q*. Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nature Biotechnology 2013 Aug;31(8):684-686. doi: 10.1038/nbt.2652.

Li W#, Shuai L#, Wan H#, Dong M#, Wang M, Sang L, Feng C, Luo GZ, Li T, Li X, Wang L, Zheng QY, Sheng C, Wu HJ, Liu Z, Liu L, Wang L, Wang XJ, Zhao XY*, Zhou Q*. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature 2012 Oct 18;490(7420):407-411. doi: 10.1038/nature11435.

Zhao XY#, Li W#, Lv Z#, Liu L, Tong M, Hai T, Hao J, Guo CL, Ma QW, Wang L, Zeng F*, Zhou Q*. iPS cells produce viable mice through tetraploid complementation. Nature 2009 Sep 3;461(7260):86-90. doi: 10.1038/nature08267.


取自“https://wiki.biodiversity.cern.ac.cn/index.php?title=李伟&oldid=30390”