王恒

性别

男

工作单位

中国医学科学院基础医学研究所

职称/职务

研究员

主要研究方向

传染病、分子寄生虫学和寄生虫基因工程疫苗

工作年限（从事该领域研究的起始时间）

28年（起始：1997）

代表性学术论文

（1）Dingding Shao1,*, Xiang Zhong1,*, Yan-Feng Zhou2,3, Zhifu Han1,4, Yahui Lin1, Zhensheng Wang1, Lingyi Bu1, Lianhui Zhang1, Xiao-Dong Su2,**, Heng Wang1,**2010，Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host， Molecular Immunology, Volume 47, Issue 4, January 2010：726-737

（2）Yuhui Gaoa, Huiliang Lib, Yan Lub, Fangming Gaoa, Yahui Lina, Hongchang Zhoua, Lianhui Zhanga, and Heng Wanga*，2009，Identification of a vaccine candidate antigen, PfMAg-1, from Plasmodium falciparum with monoclonal antibody M26-32，Parasitology Research，105:1723-32 公卫家园

（3）ZHOU Hong-chang, GAO Yu-hui, ZHONG Xiang and WANG Heng*,2009,Dynamin like protein 1 participated in the hemoglobin uptake pathway of Plasmodium falciparum,Chin Med J, 122(4), 1686-91

（4）Zhensheng Wang, Dingding Shao, Xiang Zhong, Cong Han, Pengfei Cai，Heng Wang∗，2009，Epitope mapping of monoclonal antibody 1B9 against Plasmodium falciparumderived macrophage migration inhibitory factor，Immunologinal Investigation, 38(5),422-433 公卫考场

（5）HoalinLiu， ChenggangLi， hongliang Wang, Yang Sun, Feng Guo, Shuan Rao, Jiejie Deng, Yanli Zhang, Yufa Miao, Chenying Guo, Jie Meng, Xiping Chen, Limin Li, Haiyan Xu, Heng Wang*, Bo Li*, Chengyu Jiang* (Co-correspondence), 2009, Nanoparticle promotes acute lung injury by inducing autophagic cell death through Akt-TSC2-mTOR signaling pathway, Journal of Molecular Cell Biology, 1 (1) 1, 37-45

（6）Pengfei Cai, Lingyi Bu, Jian Wang, Zhensheng Wang, Xiang Zhong, Heng Wang*，2008，

Molecular characterization of Schistosoma japonicum tegument protein tetraspanin-2: effect of sequence variation on its potential as a vaccine candidate"，Biochem Biophys Res Commun. 372（1）：197-202

（7）Dingding Shao1, Zhifu Han1, Yahui Lin1, Lianhui Zhang1, Xiang Zhong1, Manling Feng2, Heng Wang1,* 2008，Detection of Plasmodium falciparum derived macrophage migration inhibitory factor homologue in the sera of malaria patients，Act. Trap. Vol 106/1， 9-15

（8）Qiliang Cai, Guiying Peng, Lingyi Bu, Yahui Lin, Lianhui Zhang, Sara Lustigmen, Heng Wang*，2007，Immunogenicity and in vitro protective efficacy of a polyepitopePlasmodium falciparum candidate vaccine constructed by epitope shuffling, VACCINE, 25：5155－5165

（9）GUO Chen-Ying, WANG Heng*, LIN Ya-Hui, CAI Qi-Liang, 2004, Application of Starburst TM PAMAM Dendrimers as DNA Carriers In vitro, Prog. Biochem. Biophys, 31（9）：804－811

（10）L Cai, F. Wei, YH Lin, D.D. Shao, H. Wang*, 2004, Immunogenicity of polyepitope libraries assembled by epitope shuffling: an approach to the development of chimeric gene vaccination against malaria, VACCINE, 23: 267-277 公卫人

Li H, Han Z, Lu Y, Lin Y, Zhang L, Wu Y, Wang H*, 2004., Isolation and functional characterization of a dynamin-like gene from Plasmodium falciparum, Biochem Biophys Res Commun. Jul 30;320(3):664-71.