张永莲

代表论著

P. Li, H. C. Chan, B. He, S. C. So, Y. W. Chung, Q. Shang, Y. D. Zhang, and Y. L. Zhang. 2001. An antimicrobial peptide gene found in the male reproductive system of rats. Science. 291(5509): 1783-1785.

Q. Liu, K. G. Hamil, P. Sivashanmugam, G. Grossman, R. Soundararajan, A. J. Rao, R. T. Richardson, Y. L. Zhang, M. G. O’Rand, P. Petrusz, F. S. French, and S. H. Hall. 2001. Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human. Endocrinology. 142(10): 4529-4539.

Y. X. Hu, J. Y. Guo, L. Shen, Y. Chen, Z. C. Zhang, and Y. L. Zhang. 2002. Get effective polyclonal antisera in one month. Cell Res. 12(2): 157-160.

K. G. Hamil, Q. Liu, P. Sivashanmugam, S. Yenugu, R. Soundararajan, G. Grossman, R. T. Richardson, Y. L. Zhang, M. G. O’Rand, P. Petrusz, F. S. French, and S. H. Hall. 2002. Cystatin 11: a new member of the cystatin type 2 family. Endocrinology. 143(7): 2787-2796.

Y. Hu, Z. Zhou, C. Xu, Q. Shang, Y. D. Zhang, and Y. L. Zhang. 2003. Androgen down-regulated and region-specific expression of germ cell nuclear factor in mouse epididymis. Endocrinology. 144(4): 1612-1619.

C. X. Zhou, Y. L. Zhang, L. Xiao, M. Zheng, K. M. Leung, M. Y. Chan, P. S. Lo, L. L. Tsang, H. Y. Wong, L. S. Ho, Y. W. Chung, and H. C. Chan. 2004. An epididymis-specific beta-defensin is important for the initiation of sperm maturation. Nat Cell Biol. 6(5): 458-464.

J. S. Zhang, Q. Liu, Y. M. Li, S. H. Hall, F. S. French, and Y. L. Zhang. 2006. Genome-wide profiling of segmental-regulated transcriptomes in human epididymis using oligo microarray. Mol Cell Endocrinol. 250(1-2): 169-177.

H. X. Yuan, A. H. Liu, L. Zhang, H. Zhou, Y. Wang, H. Zhang, G. Wang, R. Zeng, Y. L. Zhang, and Z. J. Chen. 2006. Proteomic profiling of regionalized proteins in rat epididymis indicates consistency between specialized distribution and protein functions. J Proteome Res. 5(2): 299-307.

H. Diao, C. Y. Guo, D. H. Lin, and Y. L. Zhang. 2007. Intein-mediated expression is an effective approach in the study of beta-defensins. Biochem Biophys Res Commun. 357(4): 840-846.

C. F. Zhu, Q. Liu, L. Zhang, H. X. Yuan, W. Zhen, J. S. Zhang, Z. J. Chen, S. H. Hall, F. S. French, and Y. L. Zhang. 2007. RNase9, an androgen-dependent member of the RNase A family, is specifically expressed in the rat epididymis. Biol Reprod. 76(1): 63-73.

J. Y. Li, H. Y. Wang, J. Liu, Q. Liu, J. S. Zhang, F. C. Wan, F. J. Liu, S. H. Jin, and Y. L. Zhang. 2008. Transcriptome analysis of a cDNA library from adult human epididymis. DNA Res. 15(3): 115-122.

Y. C. Zhou, M. Zheng, Q. X. Shi, L. Zhang, W. Zhen, W. Y. Chen, and Y. L. Zhang. 2008. An epididymis-specific secretory protein HongrES1 critically regulates sperm capacitation and male fertility. PLoS One. 3(12): e4106.

W. Zhen, P. Li, B. He, J. Y. Guo, and Y. L. Zhang. 2009. The novel epididymis-specific beta-galactosidase-like gene Glb1l4 is essential in epididymal development and sperm maturation in rats. Biol Reprod. 80(4): 696-706.

D. M. Cao, Y. Li, R. Yang, Y. Wang, Y. C. Zhou, H. Diao, Y. Zhao, Y. L. Zhang, and J. Lu. 2010. Lipopolysaccharide-induced epididymitis disrupts epididymal beta-defensin expression and inhibits sperm motility in rats. Biol Reprod. 83(6): 1064-1070.

S. G. Hu, G. X. Yao, X. J. Guan, Z. M. Ni, W. B. Ma, E. M. Wilson, F. S. French, Q. Liu, and Y. L. Zhang. 2010. Research resource: Genome-wide mapping of in vivo androgen receptor binding sites in mouse epididymis. Mol Endocrinol. 24(12): 2392-2405.

Y. Zhao, H. Diao, Z. M. Ni, S. G. Hu, H. G. Yu, and Y. L. Zhang. 2011. The epididymis-specific antimicrobial peptide beta-defensin 15 is required for sperm motility and male fertility in the rat (Rattus norvegicus). Cell Mol Life Sci. 68(4): 697-708.

C. M. Wang, C. Y. Huang, Y. H. Gu, Y. C. Zhou, Z. M. Zhu, and Y. L. Zhang. 2011. Biosynthesis and distribution of Lewis X- and Lewis Y-containing glycoproteins in the murine male reproductive system. Glycobiology. 21(2): 225-234.

Y. Chen, C. Chu, Y. C. Zhou, Y. F. Ru, H. R. Chen, F. Chen, Q. J. He, Y. L. Zhang, L. L. Zhang and J. L. Shi. 2011. Reversible pore-structure evolution in hollow silica nanocapsules: large pores for siRNA delivery and nanoparticle collecting. Small. 7(20): p. 2935-44.

M. J. Ni, Z. H. Hu, Q. Liu, M. F. Liu, M. H. Lu, J. S. Zhang, L. Zhang and Y. L. Zhang. 2011. Identification and characterization of a novel non-coding RNA involved in sperm maturation. PLoS One. 6(10): e26053.

Y. L. Zhang, J. S. Zhang, Y. C. Zhou, Y. Zhao and M. J. Ni. 2011. Identification of microRNAs and application of RNA interference for gene targeting in vivo in the rat epididymis. J Androl. 32(6): 587-91.

W. B. Ma, S. S. Xie, M. J. Ni, X. X. Huang, S. G. Hu, Q. Liu, A. H. Liu, J. S. Zhang and Y. L. Zhang. 2012. MicroRNA-29a inhibited epididymal epithelial cell proliferation by targeting nuclear autoantigenic sperm protein(NASP). J Biol Chem. 287: 10189-10199.

X. Q. Li, M. J. Ni and Y. L. Zhang. 2012. Detecting miRNAs by liquid hybridization and color development. Methods. 58(2): 151-5.

S. S. Xie, J. Xu, W. B. Ma, Q. Liu, J. X. Han, G. X. Yao, X. X. Huang and Y. L. Zhang. 2013. Lcn5 promoter directs the region-specific expression of cre recombinase in caput epididymidis of transgenic mice. Biology of Reproduction. 88(3): 71.

Y. C. Zhou, Y. F. Ru, C. M. Wang, S. L. Wang, Z. M. Zhou and Y. L. Zhang. 2013. Tripeptidyl peptidase II regulates sperm function by modulating intracellular Ca(2+) stores via the ryanodine receptor. PLoS One. 8(6): e66634.

J. S. Zhang, S. S. Xie, W. B. Ma, Y. Teng, Y. Tian, X. X. Huang and Y. L. Zhang. 2013. A newly identified microRNA, mmu-miR-7578, functions as a negative regulator on inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 via targeting Egr1 in vivo. J Biol Chem. 288(6): 4310-20.

L. Ma, H. G. Yu, Z. M, Ni, S. G. Hu, W. B. Ma, C. Chu, Q. Liu and Y. L. Zhang. 2013. Spink13, an epididymis-specific gene of the Kazal-type serine protease inhibitor (SPINK) family, is essential for the acrosomal integrity and male fertility. J Biol Chem. 288(14): 10154-65.

H. G. Yu, J. Dong, Y. H. Gu, H. Y. Liu, A. J. Xin, H. J. Shi, F. Sun, Y. L. Zhang, D. H. Lin and H. Diao. 2013. The novel human beta-defensin 114 regulates lipopolysaccharide (LPS)-mediated inflammation and protects sperm from motility loss. J Biol Chem. 288(17): 12270-82.

W. B. Ma, S. G. Hu, G. X. Yao, S. S. Xie, M. J. Ni, Q. Liu, X. X. Gao, J. S. Zhang, X. X. Huang and Y. L. Zhang. 2013. An Androgen Receptor-MicroRNA-29a Regulatory Circuitry in Mouse Epididymis. J Biol Chem. 288(41): 29369-81.