索勋

性别

男

工作单位

中国农业大学

职称/职务

教授

主要研究方向

高级寄生虫学、基础生物学

工作年限（从事该领域研究的起始时间）

22年（起始：2003）

论文著作

I. 寄生虫及其他病原免疫学研究

1. El-Ashram S, Al Nasr I, El-Kemary M, Mehmood R, Hu M, Suo X. Early and late gene expression profiles of the ovine mucosa in response to Haemonchus contortus infection employing Illumina RNA-seq technology. Parasitol Int. 2017 Oct;66(5):681-692.

2. Zhu L, Zhao X, Yin Q, Liu X, Chen X, Huang C, Suo X.Mucosal IgA and IFN-γCD8 T cell immunity are important in the efficacy of live Salmonella enteria serovar Choleraesuis vaccines.Sci Rep. 2017 Apr 13;7:46408.

3. Tao G, Shi T, Tang X, Duszynski DW, Wang Y, Li C, Suo J, Tian X, Liu X, Suo X. Transgenic Eimeria magna Pérard, 1925 Displays Similar Parasitological Properties to the Wild-type Strain and Induces an Exogenous Protein-Specific Immune Response in Rabbits (Oryctolagus cuniculus L.). Front Immunol. 2017 Jan 23;8:2.

4. Tang X, Yin G, Qin M, Tao G, Suo J, Liu X, Suo X.Transgenic Eimeria tenella as a vaccine vehicle: expressing TgSAG1 elicits protective immunity against Toxoplasma gondii infections in chickens and mice. Sci Rep. 2016 Jul 8;6:29379.

5. Qin M, Tang X, Yin G, Liu X, Suo J, Tao G, Ei-Ashram S, Li Y, Suo X. Chicken IgY Fc expressed by Eimeria mitis enhances the immunogenicity of E. mitis. Parasit Vectors. 2016 Mar 21;9:164.

6. Zhu L, Feng Y, Zhang G, Jiang H, Zhang Z, Wang N, Ding J, Suo X. Brucella suis strain 2 vaccine is safe and protective against heterologous Brucella spp. infections. Vaccine. 2016 Jan 12;34(3):395-400.

7. Sun XM, Ji YS, Elashram SA, Lu ZM, Liu XY, Suo X, Chen QJ, Wang H. Identification of antigenic proteins of Toxoplasma gondii RH strain recognized by human immunoglobulin G using immunoproteomics. J Proteomics. 2012 Dec 21;77:423-32.

8. Huang X, Zou J, Xu H, Ding Y, Yin G, Liu X, Suo X. Transgenic Eimeria tenella expressing enhanced yellow fluorescent protein targeted to different cellular compartments stimulated dichotomic immune responses in chickens. J Immunol. 2011 Oct 1;187(7):3595-602.

II. 寄生虫基因编辑及遗传研究平台构建

9. Tang X, Liu X, Tao G, Qin M, Yin G, Suo J, Suo X. "Self-cleaving" 2A peptide from porcine teschovirus-1 mediates cleavage of dual fluorescent proteins in transgenic Eimeria tenella. Vet Res. 2016 Jun 28;47(1):68.

10. Shi T, Tao G, Bao G, Suo J, Hao L, Fu Y, Suo X. Stable Transfection of Eimeria intestinalis and Investigation of Its Life Cycle, Reproduction and Immunogenicity. Front Microbiol. 2016 May 31;7:807.

11. Yin G, Liu X, Zou J, Huang X, Suo X. Co-expression of reporter genes in the widespread pathogen Eimeria tenella using a double-cassette expression vector strategy. Int J Parasitol. 2011 Jul;41(8):813-6.

12. Zou J, Liu X, Shi T, Huang X, Wang H, Hao L, Yin G, Suo X.Transfection of Eimeria and Toxoplasma using heterologous regulatory sequences. Int J Parasitol. 2009 Sep;39(11):1189-93.

13. Liu X, Shi T, Ren H, Su H, Yan W, Suo X. Restriction enzyme-mediated transfection improved transfection efficiency in vitro in Apicomplexan parasite Eimeria tenella. Mol Biochem Parasitol. 2008 Sep;161(1):72-5.

14. Hao L, Liu X, Zhou X, Li J, Suo X. Transient transfection of Eimeria tenella using yellow or red fluorescent protein as a marker. Mol Biochem Parasitol. 2007 Jun;153(2):213-5.

III. 传统寄生虫学研究

15. Li Z, Guo Q, Zheng L, Ji Y, Xie YT, Lai DH, Lun ZR, Suo X, Gao N. Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii. Cell Res. 2017 Aug 15.

16. Cui P, Liu H, Fang S, Gu X, Wang P, Liu C, Tao G, Liu X, Suo X.A new species of Eimeria (Apicomplexa: Eimeriidae) from Californian rabbits in Hebei Province, China. Parasitol Int. 2017 Oct;66(5):677-680.

17. El-Ashram S, Suo X. Exploring the microbial community (microflora) associated with ovine Haemonchus contortus (macroflora) field strains. Sci Rep. 2017 Mar 6;7(1):70.

18. El-Ashram S, Suo X. Electrical cream separator coupled with vacuum filtration for the purification of eimerian oocysts and trichostronglyid eggs. Sci Rep. 2017 Feb 24;7:43346.

19. Sun XM, Ji YS, Liu XY, Xiang M, He G, Xie L, Suo JX, Suo X.Improvement and Evaluation of Loop-Mediated Isothermal Amplification for Rapid Detection of Toxoplasma gondii Infection in Human Blood Samples. PLoS One. 2017 Jan 5;12(1):e0169125.

IV. 国际合作论文：

20. Kong P, Ufermann CM, Zimmermann DLM, Yin Q, Suo X, Helms JB, Brouwers JF, Gupta N. Two phylogenetically and compartmentally distinct CDP-diacylglycerol synthases cooperate for lipid biogenesis in Toxoplasma gondii. J Biol Chem. 2017 Apr 28;292(17):7145-7159.

21. Clark EL, Macdonald SE, Thenmozhi V, Kundu K, Garg R, Kumar S, Ayoade S, Fornace KM, Jatau ID, Moftah A, Nolan MJ, Sudhakar NR, Adebambo AO, Lawal IA, Álvarez Zapata R, Awuni JA, Chapman HD, Karimuribo E, Mugasa CM, Namangala B, Rushton J, Suo X, Thangaraj K, Srinivasa Rao AS, Tewari AK, Banerjee PS, Dhinakar Raj G, Raman M, Tomley FM, Blake DP.

Cryptic Eimeria genotypes are common across the southern but not northern hemisphere. Int J Parasitol. 2016 Aug;46(9):537-44.

22. Lee SH, Dong X, Lillehoj HS, Lamont SJ, Suo X, Kim DK, Lee KW, Hong YH. Comparing the immune responses of two genetically B-complex disparate Fayoumi chicken lines to Eimeria tenella. Br Poult Sci. 2016 Apr;57(2):165-71.

23. Su H, Liu X, Yan W, Shi T, Zhao X, Blake DP, Tomley FM, Suo X. piggyBac transposon-mediated transgenesis in the apicomplexan parasite Eimeria tenella. PLoS One. 2012;7(6):e40075.

24. Dong X, Abdelnabi GH, Lee SH, Li G, Jin H, Lillehoj HS, Suo X.Enhanced egress of intracellular Eimeria tenella sporozoites by splenic lymphocytes from coccidian-infected chickens. Infect Immun. 2011 Aug;79(8):3465-70.

25. Yan W, Liu X, Shi T, Hao L, Tomley FM, Suo X. Stable transfection of Eimeria tenella: constitutive expression of the YFP-YFP molecule throughout the life cycle. Int J Parasitol. 2009 Jan;39(1):109-17.